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Antibiotics encoded in Neanderthal DNA could help us fight infections

A search of the ancient DNA of Neanderthals and Denisovans has revealed coding for extinct bacteria-killing proteins that we could revive to fight infections

By Carissa Wong

1 December 2022

A recreation of a Neanderthal man

Ancient humans such as Neanderthals had bodily defences against bacteria that might help us treat infections nowadays

SEBASTIAN WILLNOW/DDP/AFP via Getty Images

Reviving extinct antibiotic molecules encoded in the DNA of Neanderthals and Denisovans could provide a new weapon in the fight against antimicrobial resistance.

Last year, at the University of Pennsylvania and his colleagues reported on .

Now, de la Fuente and many of the same researchers have identified six more antibiotic peptides encoded in ancient mitochondrial DNA previously extracted from Neanderthals and Denisovans…

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