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How to defeat the disease that killed half the people who ever lived

Malaria is humanity's greatest scourge. But genetic technologies that threaten to send mosquitoes extinct are problematic, and no substitute for practical action now

21 August 2019

91av. Science news and long reads from expert journalists, covering developments in science, technology, health and the environment on the website and the magazine.

The plasmodium parasites that cause malaria may have killed half of all humans

Dr Tony Brain/Science Photo Linraey

IN ROME 1500 years ago, a mysterious plague swept through the city. Of the hundreds of children killed, one was buried in a cemetery on the outskirts of the city. In 2001, her body was exhumed and autopsied using modern genetic techniques. The tests showed she had died of malaria – the case of a disease that has been with us since time immemorial.

Malaria may have killed perhaps half of all the people who have ever lived. For most…

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