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Putting the DIY in DNA

By Jonathon Keats

6 April 2011

Part field guide and part critique, Marcus Wohlsen’s Biopunk navigates the contentious new terrain of biohacking

WHEN her dad was diagnosed with the hereditary disease haemochromatosis, 23-year-old Kay Aull did the natural thing, at least for an MIT graduate in bioengineering. She went online and bought a used thermal cycler for $100. She also ordered several custom-made DNA sequences, designing each to bind to a different mutation of the gene responsible for the disease. Then, using other second-hand equipment she had acquired, she set up a simple lab test in her closet and determined the likelihood that she would inherit…

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