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Life still goes on without 'vital' DNA

By Sylvia Pagán Westphal

5 June 2004

IT’S not often that the audience at a scientific meeting gasps in amazement during a talk. But that’s what happened recently when researchers revealed that they had deleted huge chunks of the genome of mice without it making any discernable difference to the animals. The result is totally unexpected because the deleted sequences included so-called “conserved regions” thought to have important functions.

All DNA tends to acquire random mutations, but if these occur in a region that has an important function, individuals will not survive. Key sequences should thus remain virtually unchanged, even between species. So by comparing the genomes…

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