Remove and replace Science / Alamy Stock Photo
The CRISPR genome-editing method may just have become even more powerful. ’s team at McGill University in Canada has managed to repair mutations in 90 per cent of target cells using CRISPR – the best success rate yet.
The CRISPR approach is very good at disabling genes, but using the technique to fix them is much harder, because it involves replacing a faulty sequence with another. This typically works in less than 10 per cent of target cells.
To make the process more efficient, Akavia’s team physically linked the replacement…
