These striking photographs tell a deadly story about climate change and dengue fever, generally the world’s fastest-spreading mosquito-borne disease.

Photographer ’s photo essay The Ascent of Temperatures explores how dengue has spread to Nepal’s Himalayan districts, including Chandannath, which, at 2438 metres above sea level, is one of the highest towns where Aedes aegypti and Aedes albopictus mosquitoes and their larvae have been discovered. Previously, these mosquitoes, which transmit dengue and other diseases, had been observed only at elevations of up to 2100 metres, according to the photographer.

Segalerba has been exploring “how traditional knowledge systems respond to external pressures”, and was investigating the spread of dengue into high-altitude areas in the Peruvian Andes when he learned of what was happening in Nepal. “It turned out to be the clearest setting for that question: a millennia-old medical tradition with its own framework for understanding illness, suddenly facing a disease it had never encountered before,” he says.

Recently, dengue has spread across most of Nepal, fuelled by climate change as well as increasing travel. According to , at least six people died of dengue in 2025 and around 9000 were infected, with the virus now having spread to 76 out of the country’s 77 districts.

Above, a female Aedes aegypti mosquito is shown in detail under a microscope. The Nepal Health Research Council (NHRC), working with the Institute of Tropical Medicine in Antwerp, Belgium, examines larvae and adult mosquitoes for changes in colour or shape that show they are becoming resistant to insecticides or adapting to different altitudes.

Below, Ishan Gautam, associate professor and chief of the Natural History Museum at Tribhuvan University in Kathmandu, shows Aedes larvae to students at Geetamata Secondary School, also in Kathmandu. The university organises awareness campaigns where local people are shown live Aedes mosquito larvae, and learn about their breeding habits and the importance of removing potential breeding sites like stagnant water.

In the image below, Amchi Khedup Loden Gurung packs traditional Sowa Rigpa (Tibetan) medicines in a clinic in Jomsom, northern Nepal.

Mosquito nets are being encouraged around Chandannath: below, local resident Devi Kannya Katayata breastfeeds her son Nehan Budha under a net at home.

In the image below, Sunita Baral, a PhD student at the NHRC, examines a mosquito inside a rearing cage. The council studies larvae and adult specimens from many habitats to discover more about the dengue-carrying mosquitoes circulating across Nepal.

Below, sheets are seen drying in the sun in the courtyard of Pokhara Hospital. Pokhara is the main gateway to the high-altitude region of Mustang, where Segalerba says dengue cases have recently been reported. Experts fear reported cases are a small fraction of the true infection level, he says, because around 90 per cent of infected people are asymptomatic, and many cases and deaths may go unreported.

Researchers have found the first probiotic treatment that stops or slows a disease that has been killing Caribbean corals, and prevents its spread to healthy corals. The new approach provides an alternative to currently used amoxicillin treatments without the risk of promoting antibiotic-resistant bacteria in the sea.

Stony coral tissue loss disease (SCTLD) has mystified scientists since it was discovered in Florida reefs in 2014. The pathogen causing it appears to spread rapidly through seawater. It has now killed hard corals – the reef-building corals with bony skeletons – in almost every stretch of the Caribbean.

“It’s creating what are essentially open wounds in the corals that eventually will spread and consume the coral until all you have left is a skeleton,” says at the University of North Carolina Wilmington. But Ushijima and his colleagues noticed that, even when infected, some fragments of great star coral (Montastraea cavernosa) never got sick. They collected samples of 222 bacterial strains on those disease-resistant fragments and found 83 had some antimicrobial activity, including a strain called McH1-7 that was particularly active.

When the researchers dosed live corals with McH1-7 and tented them inside a plastic bag, they found the probiotic treatment stopped or slowed the progression of SCTLD in 68 per cent of 22 infected coral fragments.

“More amazingly, it seems to protect healthy corals from infection,” says Ushijima. In their 12 lab trials, the probiotic prevented SCTLD from spreading to healthy corals, something antibiotics are not able to do. Because stony coral species are numerous and diverse, “it’s likely each species will need its own treatment”, says Ushijima.

Probiotics could also provide longer-term protection than amoxicillin paste, which is currently spread onto corals by hand, says at the Smithsonian Marine Station in Fort Pierce, Florida. “The hope is that the probiotic can become incorporated into the coral’s microbiome and provide more lasting protection against disease.”

The treatment is now being tested on corals in the wild at reefs near Fort Lauderdale, Florida, and in the Florida Keys.